flexible. precise. affordable

Impedance Meters & Impedance Spectroscopy

Sciospec develops impedance analyzers for different applications. They are available in many different models to meet your specific needs. Our experienced specialists will be happy to advise you on which model best suits your application. In addition, our application consultants can help you specify and implement application-specific solutions based on our modular technology platform. Combined with customized software, there are no limits to your ability to realize individual impedance analyzer systems that fit your specific application environment. For industrial customers, we also offer the Sciospec technology proven in our laboratory instruments on an OEM basis. This makes it easy to integrate our core technology, electrical impedance spectroscopy, into your product or solution.

ISX-3 with extension port cable
Single channel impedance analyzer for daily laboratory use.
Two-channel impedance analyzer for research and field use.
Multi-channel impedance analyzer for demanding research applications. Fully parallel ultrafast measurements for higher throughput.

Available options

  • Connectors : BNC, SMA, MCX, DSUB ...
  • internal multiplexer for sequential multi-channel measurements
    • 32 x 2-point measurement
    • 16 x 4 point measurement
  • IOport digital interfaces for external sensors or peripheral hardware
  • Wireless interfaces
  • Extras for safety according to medical standards
    • Power supply
    • Insulated housing
    • Isolated USB port
    • AC-coupled front end
  • Temperature measurement module
  • high-precision multi-channel temperature measurement module for common temperature sensor types
  • Customizable current and voltage ranges
  • 2nd measuring channel (standard in ISX-3 mini / optional for ISX-3)
  • Battery operated
  • and many more

Impedance analyzers - chip adapters and multiplexers

  • Adapter for multi-electrode arrays (MEAs) and other sensors / biochips
  • 64-channel analog multiplexer
  • 60 gold spring contacts
  • Layout suitable for a variety of commercially available chips
  • Chip development for special applications on request
  • small and flat
  • Bottom and lid fixtures allow the combination with optical processes
  • easy installation via the ExtensionPort
  • fully integrated in Sciospec software and the user interface

see the product page for more information

  • Adapter for ECIS 8-well chips for connection to a Sciospec impedance analyzer
  • 8 channels - each in 2-point configuration (8 working electrodes and a common counter electrode)
  • Layout suitable for a wide range of ECIS 8-well sensors
  • small and flat
  • suitable for operation in the incubator
  • Glass bottom enables the combination with optical processes
  • easy installation via the ExtensionPort
  • fully integrated in Sciospec software and the user interface

see the product page for more information

  • 50-port 2- / 3- / 4-point multiplexer for Sciospec impedance analyzers (e.g. ISX-3)
  • very robust, low-parasitic card connector for plug-in cards
  • small, flat, incubator-safe
  • flexible options for your sensors
    • Contacts on your sensor substrate or on the sensor carrier (e.g. PCB-based)
    • Cable adapter
    • Sensor carriers can be ordered from us
    • design and build your own sensor
    • or let us do the design
  • easy installation via the ExtensionPort
  • fully integrated in Sciospec software and the user interface

see the product page for more information

Still not 100 percent suitable for your application? Then let us tailor it for you!

Our modular platform enables an inexpensive implementation of customer requests with minimal development risk So what would you wish for? An application-specific multiplexer solution, a portable device for a health monitoring application or a massive multi-channel platform for screening and QA in component manufacturing or pharmaceuticals? Feel free to contact us!

Impedance meters and impedance measurement from Sciospec!

Where is Sciospec's technology used?

Our primary fields of application are in bioanalytics, material analysis and process measurement technology. This is where our laboratory measuring instruments can be found. But our platform can do more:
From the smallest biosensor and point-of-care solutions to multi-channel biochip systems and massive multi-channel solutions for automated process testing or pharmacological testing applications - scalability is in our genes. Sciospec technology in the form of OEM solutions is at the heart of numerous products for bioanalytical, medical and industrial applications. At the same time, our easily customizable products enable breakthrough medical and pharmacological research, inspire the next generation of manufacturing processes, and provide previously unthinkable scalability in automated component testing anywhere in the world.

What is an impedance measurement?

Electrical impedance spectroscopy enables the characterization of the electrical or dielectric properties of a device under test (DUT). In contrast to a pure DC or common mode measurement of resistance, electrical impedance spectroscopy captures the complex impedance - represented by magnitude and phase or real and imaginary components as a function of frequency. Depending on the field of application, one speaks of impedance spectroscopy, complex impedance analysis, AC resistance measurement or dielectric spectroscopy - but ultimately always the same is meant: the measurement of frequency-dependent complex impedances. The underlying electrical material properties include: Dielectric properties. They are a significant component of characteristic material parameters. This applies to all types of materials - technically used as well as biological, solid as well as liquid or gaseous. In many cases, the electrical properties allow drawing conclusions about the structural and functional properties of materials, components, but also biological tissues or even more complex entities such as organs. In addition to the analysis of existing structures or objects, electrical impedance is also frequently used as a mediating variable for sensors. While the target parameter to be detected is, for example, a gas concentration, a mass or the presence of certain pathogens, an electrical impedance is first measured at the sensor. In such cases, this is often not the impedance of the target object to be detected (e.g. the gas), but that of a "mediator" (also known as a "transducer"). This can be, for example, a functional layer on the sensor, which changes its electrical properties depending on the target substance. In this way, even elusive parameters become measurable with the easily manageable electrical measurement. The use of electrical impedance spectroscopy thus extends over a very wide field, from materials science and environmental sensing to the testing of technical components, bioanalytics and clinical diagnostics.

Examples of application areas

Bioanalysis - cell biological assays

From the smallest biosensor and point-of-care solutions to multi-channel biochip systems and massive multi-channel solutions for automated process control or pharmacological testing applications - scalability is in our genes. Bioanalytics have always represented the largest share of our use cases. The most typical representative are applications based on cell cultures - so-called cell-based assays. The cell cultures can either grow on substrates with electrode structures or be in flow-through (e.g. in microfluidic channels). Three-dimensional arrangements of cell clusters and electrodes are also becoming increasingly common, as is particularly relevant in so-called organ-on-chip applications. The electrical impedance of cell clusters or, in some cases, individual cells is measured. The electrical properties allow conclusions to be drawn about the structure or the physiological state. Dynamic physiological activity such as the "beating" of heart muscle cells (cardiomyocytes) or the typing of cell types in flow channels are also typical application scenarios for impedance spectroscopy. Specific derived parameters are often extracted from the impedance data - for example the TEER (trans epitelial electrical resistance) or growth parameters such as tissue density. The potential applications of such cell biological assays are far-reaching. Particularly exciting representatives are efficacy and tolerability testing of pharmaceutical agents and clinical diagnostics, e.g. phenotyping of risk groups for certain neurodegenerative or cardiovascular diseases. Sciospec has always worked intensively with specialized partners in bioanalytics and has developed numerous OEM products for this purpose over the years.

Medical technology - clinical diagnostics

Not only cell cultures and removed tissue have electrical properties that can be used diagnostically. Complex biological entities ranging from artificial organs to patients can also be examined with impedance spectroscopy. A particularly illustrative example is impedance tomography for monitoring lung and heart activity. Electrical impedance (typically viewed here as complex conductivity) is used to perform imaging analyses. This can be used to derive parameters important for artificial ventilation, for example, or indicators of impending traumatic events for lung and heart functionality.

Component testing

The testing of passive and active electrical components such as resistors, capacitors and miniature energy storage devices poses increasing challenges for their manufacturers. On the one hand, these components must be specified more and more extensively in data sheets, and on the other hand, it must be possible to verify these specifications in production. This results from the rapidly increasing requirements of electronic products for the mass market. Whereas a few years ago it was only necessary to install very precise components in the development of price-intensive products, now articles in the consumer sector with high quality requirements are also in demand. Whereas until a few years ago RLC test equipment with a single frequency measurement on a few samples per production batch was typically sufficient, today more and more components with complex frequency-resolved impedance characteristics have to be tested. In addition, test quotas have risen sharply: In the example of miniature energy storage devices, which are increasingly needed in the current IoT trend, test rates of 100% are required due to the electrical conditioning and susceptibility to interference. The combination of application-specific high-precision impedance spectroscopy and high channel count is an excellent fit for Sciospec's product portfolio.

Materials science

In the development and testing of materials, the electrical properties factually always play at least a secondary role, in many cases they are even the primary focus. Very typical examples are functional surface coatings, materials for the construction of technical systems or substrates for energy storage. Since the electrical properties are a decisive factor in determining how suitable a material is for a particular application, impedance spectroscopy plays an essential role during the development and production of the materials.

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