Parametric Imaging with EIT: New Approaches in Impedance-Based Functional Diagnostics

Parametric Imaging with EIT: New Approaches in Impedance-Based Functional Diagnostics
Parametric Imaging with EIT: New Approaches in Impedance-Based Functional Diagnostics

New Frontiers in Biomedical Imaging with Parametric EIT

Electrical impedance tomography (EIT) continues to expand the boundaries of biomedical imaging and the latest research from North-western University shows just how powerful parametric approaches to EIT can be. In the study titled “Parametric EIT inversion with sparse model sampling” researchers demonstrate a novel methodology for imaging internal structures using significantly fewer impedance measurements than traditional EIT reconstructions. This work leveraged Sciospec’s EIT128 system showing how scalable and high-performance impedance measurement technology can drive forward efficient imaging methods.

*Sheflin, J., Bah, A., Ganeshan, S. K., Onsager, C. C., Sahakian, A., Bulst, M., & Grayson, M. A. Parametric EIT inversion with sparse model sampling. IOPscience (2024). https://iopscience.iop.org/article/10.1088/1742-6596/3014/1/012020/meta

Efficient Real-Time Imaging Powered by Sciospec EIT Technology

The study explores a parametric imaging method that reconstructs object size and position from a sparse set of measurement. This innovation points toward more efficient real-time imaging solutions for applications where traditional tomographic reconstruction can be slow or data-heavy. At the heart of this experiment was a Sciospec EIT system, enabling high-resolution, multi-channel impedance data acquisition.

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Top view of a saltwater phantom tank with silver/silver chloride electrodes arranged around the edge and a test cylinder placed inside, used with the Sciospec EIT128 system for parametric imaging research.
(a) Top view of saltwater tray phantom with 15 silver/silver chloride electrodes arranged circumferentially. (b) Test cylinders of varying diameters (1.7", 2.2", 2.7", 3.2") used for training and evaluation in parametric EIT imaging.
A series of images showing insulating cylinders of various diameters placed at different angular positions inside a saltwater phantom, with parametric EIT reconstructions indicating predicted size and orientation using sparse impedance data collected via the Sciospec EIT128 system.
Parameterized reconstruction from sparse training data. (a) Single cylinder (D = 1.7”) placed at three angular positions, with actual and predicted positions (dashed circles) shown. (b)–(d) Reconstructions for cylinders of diameters 2.2”, 2.7”, and 3.2”. (e) Left: single angular placement of the 3.2” cylinder.

Why This Research Matters: Imaging with Fewer Measurements

Conventional EIT methods rely on generating full conductivity maps through dense datasets and significant computational effort. While effective, these methods can be inefficient, especially in cases where the anatomical or physiological structure of interest can be parameterized

In the study, Sheflin et al. tested a model in which only nine optimized impedance measurements were used to determine the angular position and diameter of insulating cylinders placed in a saltwater phantom. Instead of reconstructing a full conductivity image the method directly inverted the data into a set of parameters describing the object’s size and position significantly reducing data requirements while maintaining high spatial accuracy.

The use of a Sciospec EIT128 system enabled real-time acquisition and precise signal capture across 128 channels, demonstrating how high-density impedance data can power a smarter, more efficient inversion model.

⚡Looking for more answers ? Check out our detailed FAQ section further down see how our EIT solutions are transforming Parametric Imaging

Sciospec’s Contribution: Enabling Advanced EIT Inversion with the EIT128

For this research, Sciospec provided the 128-channel EIT platform that formed the foundation for data acquisition and model validation. The experiment used true-parallel impedance measurements to collect high-fidelity voltage data from 15 electrodes placed around the imaging phantom. Thanks to our system’s capability for simultaneous sampling across all channels and flexible current injection configurations, the research team was able to:

  • Collect high-accuracy data using just a fraction of traditional measurement sets
  • Perform multi-frequency spectral measurements with sweeping  from 100 Hz to 1 MHz
  • Inject currents up to 10 mA peak amplitude accommodating a variety of conductivity scenarios
  • Achieve frame rates  up to 100 fps  suitable for dynamic physiological processes

In parametric approaches where each measurement must be highly informative, this level of performance is essential

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👉 Explore our detailed publication on Electrical Impedance Imaging using the Sciospec EIT system and learn how it drives innovation in imaging technology: Electrical Impedance Imaging with Sciospec EIT System

Sciospec EIT128 system used in parametric imaging research, featuring 128 channels for simultaneous impedance data acquisition, supporting multi-frequency measurements and high-speed frame rates up to 100 fps.
Sciospec EIT128 device showcasing a modular, 128-channel platform for electrical impedance tomography with high frame rate, flexible electrode support, and integration options for advanced imaging research.

The EIT128 Sustem: Power, Flexibility, and Scalability for EIT Research

Sciospec’s EIT32/64/128 platform is designed to provide researchers with a flexible, scalable solution for innovative EIT applications. The device used in this study , the EIT128 ,offers full compatibility with various electrode configurations and is ideally suited for tomographic imaging tasks in constrained biological or physical systems.

Key advantages of the EIT128 system include:

  • 💡  128 Channels Fully Parallel : Capture complex spatial patterns in real time with minimal signal lag.
  • ⚡ 100 fps Frame Rate : Ideal for dynamic or time-sensitive imaging scenarios.
  • 🔄  Flexible Current Injection & Voltage Sensing : Match any phantom or in-vivo setup without hardware modifications.
  • 🧠  Open Integration : Use your favorite tools (e.g., EIDORS, MATLAB) or tap into our API for custom analysis.

Our EIT systems are accompanied by a range of accessories such as phantom tanks, cable sets, and chip adapters making it easy for research teams to get started quickly and focus on results.

This modularity and adaptability ensure that setups like the one used by Sheflin et al. can scale with research needs, transitioning from simplified phantom models to more complex anatomical structures or clinical applications.

⚙️ Looking to scale or customize? Explore the full range of Sciospec EIT solutions

Scalable Solutions for Evolving Research Needs

One of the standout features of the Sciospec platform is its scalability. The same base system architecture supports EIT16, EIT32, EIT64, EIT128, and even EIT256 configurations. In this study, researchers could begin with a modest channel count and scale up to full 128-channel operation without needing to change their entire setup.

This makes the platform ideal for:

  • Feasibility studies  and rapid prototyping
  • In-vitro and phantom experiments
  • In-vivo functional imaging  in research contexts
  • Development of clinical diagnostic tools

As the need for resolution or electrode density grows the same software environment, hardware interfaces, and signal processing capabilities apply simplifying the transition between research phases.

⚙️ Want to configure your perfect EIT setup? See the advantages of our EIT systems 

Sciospec EIT128 device connected to a phantom tank, demonstrating scalable EIT imaging from low to high channel counts, adaptable for in-vitro, in-vivo, and clinical research applications.
Sciospec support team ready to assist researchers with advanced EIS solutions for ion channel studies

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Frequently Asked Questions (FAQ)

Parametric inversion in EIT refers to a technique where the internal conductivity distribution is modeled using a set of parameters, such as the size, shape, and position of anomalies. Instead of reconstructing the entire conductivity image, this method estimates these parameters directly from the measured data, leading to faster computations and reduced data requirement

Parametric inversion in EIT focuses on estimating specific parameters (like size, position, or shape of an inclusion) rather than reconstructing full conductivity images. This approach reduces computational complexity, requires fewer measurements, and can offer faster and more robust solutions, especially in scenarios where the region of interest can be described with a limited set of parameters.

Sparse model sampling leverages the idea that many physiological structures can be represented with a limited number of parameters. By focusing on these key parameters and using fewer measurements, sparse sampling enhances imaging speed and efficiency without significantly compromising accuracy. This method is particularly beneficial in real-time monitoring applications.

EIT reconstruction algorithms face several challenges, including the ill-posedness of the inverse problem, sensitivity to measurement noise, and the need for accurate modeling of the measurement system. Addressing these challenges requires advanced mathematical techniques, regularization methods, and efficient computational algorithms to achieve reliable and accurate reconstructions.

In biomedical imaging, EIT is used for monitoring and diagnosing various physiological conditions. Applications include lung function monitoring, detecting breast tumors, assessing brain activity, and evaluating tissue perfusion. Its non-invasive nature, portability, and real-time imaging capabilities make EIT a valuable tool in clinical settings.

Multi-channel impedance measurement is crucial in EIT as it allows simultaneous data acquisition from multiple electrode pairs. This capability enhances spatial resolution, improves signal-to-noise ratio, and enables real-time imaging, making it essential for dynamic monitoring and applications requiring high temporal resolution.

Phantom models in EIT are artificial constructs that simulate the electrical properties of biological tissues. They are used for calibrating and testing EIT systems, validating reconstruction algorithms, and training purposes. Phantoms provide a controlled environment to assess system performance and improve imaging techniques before clinical application.

A Smarter Path Forward for EIT-Based Imaging

The work by Sheflin et al. showcases the potential of parametric inversion techniques in EIT to reduce data loads and speed up image interpretation. This is particularly promising for applications in which the structures of interest are known or constrained

Thanks to the precision, speed, and scalability of the Sciospec EIT128 system, this research was able to validate an efficient new approach to impedance imaging that may shape the future of real-time diagnostics. As researchers continue exploring smarter imaging strategies, we’re proud that our tools are helping them lead the way.

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#Innovation  #Sciospec #ImpedanceTomography  #ElectricalImpedanceImaging #ParametricEITInversion #SparseModelSampling #Real-TimeImaging

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